NOD2 and DOCK7

  • Data Source:
  • BioGRID (two hybrid, fluorescent resonance energy transfer)

NOD2

DOCK7

Description nucleotide binding oligomerization domain containing 2 dedicator of cytokinesis 7
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Cholesterol, total ( 28270201 19060911 25961943 20686565)
  • Crohn's disease ( 28067908)
  • HDL cholesterol ( 30275531)
  • HDL cholesterol levels ( 32203549)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol ( 19060911 30275531 25961943 20686565)
  • LDL cholesterol levels ( 32203549 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Lipid traits ( 24386095)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Mean platelet volume ( 32888494)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolite levels ( 23823483 22916037)
  • Metabolite levels (lipid measures) ( 27005778)
  • Platelet distribution width ( 32888494 27863252)
  • Pneumococcal bacteremia ( 27236921)
  • Regular attendance at a gym or sports club ( 29970889)
  • Serum metabolite levels ( 31636271)
  • Serum metabolite levels (CMS) ( 31636271)
  • Total cholesterol levels ( 29403010 30275531)
  • Triglyceride levels ( 32154731 31170924 29403010 29615537 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 18193044 20864672 19060911 25961943 20686565)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes 38 interacting genes: ALPI ANKHD1 ANXA2 ATG16L1 C10orf67 CCL13 CHMP4B CHMP5 DCTN1 DOCK7 ENTR1 ERBIN GOLGA6L5P GOLGB1 HAP1 IKBIP IRGM LDOC1 LMNA LURAP1L MAP3K7 NLRC4 PDLIM5 PPP1R12C PPP2R3B PRR16 RIPK2 RPL13A SCYL1 TACC3 TNIP1 TPM1 TPM3 TPM4 TRIM41 VCP WBP11 XIAP 18 interacting genes: ANXA7 BCL2L1 CDC42 CDKN1A GRB7 NOD2 NSD3 PPP2CB PRNP RAC1 RHOA RPP14 SMN1 SNCA TK1 TRIM55 TRIM63 YWHAG
Entrez ID 64127 85440
HPRD ID 05810 16833
Ensembl ID ENSG00000167207 ENSG00000116641
Uniprot IDs A0A286YF65 Q9HC29 Q96N67
PDB IDs 6AJ4 6AJL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?