MAGEF1 and NSMCE1

Data Source:
BioGRID (pull down, pull down, affinity chromatography technology)

		MAGEF1	NSMCE1
Description		MAGE family member F1	NSE1 homolog, SMC5-SMC6 complex component
Image		No pdb structure
GO Annotations	Cellular Component		Chromosome, Telomeric Region Nucleus Nucleoplasm Smc5-Smc6 Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Protein Dimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination Protein Maturation By Iron-sulfur Cluster Transfer Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process	Double-strand Break Repair Via Homologous Recombination Postreplication Repair Protein Ubiquitination Intracellular Signal Transduction Positive Regulation Of Response To DNA Damage Stimulus
Pathways			SUMOylation of DNA damage response and repair proteins
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 30361487) Nose size ( 27182965)	Allergic disease (asthma, hay fever or eczema) ( 29679657) Asthma ( 31959851 31619474) Gut microbiota (bacterial taxa) ( 27723756) Medication use (adrenergics, inhalants) ( 31015401) Night sleep phenotypes ( 27126917) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954)
Interacting Genes		6 interacting genes: MDFI MMS19 NSMCE1 PHF7 TRAIP TRIM27	5 interacting genes: ERBB3 MAGEF1 NSMCE3 UBC UBE2D2
Entrez ID		64110	197370
HPRD ID		14348	17648
Ensembl ID		ENSG00000177383	ENSG00000169189
Uniprot IDs		Q9HAY2	Q8WV22
PDB IDs			2CT0 5HVQ 5WY5
Enriched GO Terms of Interacting Partners?
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