NSMCE1 and MAGEF1

Data Source:
BioGRID (pull down, pull down, affinity chromatography technology)

		NSMCE1	MAGEF1
Description		NSE1 homolog, SMC5-SMC6 complex component	MAGE family member F1
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Smc5-Smc6 Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Protein Dimerization Activity Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Postreplication Repair Protein Ubiquitination Intracellular Signal Transduction Positive Regulation Of Response To DNA Damage Stimulus	Protein Ubiquitination Protein Maturation By Iron-sulfur Cluster Transfer Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways		SUMOylation of DNA damage response and repair proteins
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Asthma ( 31959851 31619474) Gut microbiota (bacterial taxa) ( 27723756) Medication use (adrenergics, inhalants) ( 31015401) Night sleep phenotypes ( 27126917) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954)	Cerebral amyloid deposition (PET imaging) ( 30361487) Nose size ( 27182965)
Interacting Genes		5 interacting genes: ERBB3 MAGEF1 NSMCE3 UBC UBE2D2	6 interacting genes: MDFI MMS19 NSMCE1 PHF7 TRAIP TRIM27
Entrez ID		197370	64110
HPRD ID		17648	14348
Ensembl ID		ENSG00000169189	ENSG00000177383
Uniprot IDs		Q8WV22	Q9HAY2
PDB IDs		2CT0 5HVQ 5WY5
Enriched GO Terms of Interacting Partners?
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