MAGEF1 and TRAIP

Data Source:
BioGRID (two hybrid)

		MAGEF1	TRAIP
Description		MAGE family member F1	TRAF interacting protein
Image		No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Nucleolus Perinuclear Region Of Cytoplasm Site Of DNA Damage
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination Protein Maturation By Iron-sulfur Cluster Transfer Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process	Apoptotic Process Cellular Response To DNA Damage Stimulus Signal Transduction Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein Ubiquitination Replication Fork Processing Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interferon-beta Production Protein-DNA Covalent Cross-linking Repair
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 30361487) Nose size ( 27182965)	Blood protein levels ( 29875488 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) C-reactive protein levels ( 30388399) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mental health study participation (provided email address) ( 31263887) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tea consumption ( 31046077)
Interacting Genes		6 interacting genes: MDFI MMS19 NSMCE1 PHF7 TRAIP TRIM27	28 interacting genes: ALOX15B APP CEP19 CYLD FLII LXN MAGEF1 MAPRE2 MAPRE3 POLK POLR1C RNF114 RNF4 TNFRSF1B TRAF1 TRAF2 TRIM23 TRIM41 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2K UBE2U UBE2Z UBOX5 USP2
Entrez ID		64110	10293
HPRD ID		14348	05811
Ensembl ID		ENSG00000177383	ENSG00000183763
Uniprot IDs		Q9HAY2	Q9BWF2
PDB IDs			4ZTD
Enriched GO Terms of Interacting Partners?
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