TRAIP and MAGEF1

Data Source:
BioGRID (two hybrid)

		TRAIP	MAGEF1
Description		TRAF interacting protein	MAGE family member F1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Perinuclear Region Of Cytoplasm Site Of DNA Damage
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Apoptotic Process Cellular Response To DNA Damage Stimulus Signal Transduction Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein Ubiquitination Replication Fork Processing Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interferon-beta Production Protein-DNA Covalent Cross-linking Repair	Protein Ubiquitination Protein Maturation By Iron-sulfur Cluster Transfer Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) C-reactive protein levels ( 30388399) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mental health study participation (provided email address) ( 31263887) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tea consumption ( 31046077)	Cerebral amyloid deposition (PET imaging) ( 30361487) Nose size ( 27182965)
Interacting Genes		28 interacting genes: ALOX15B APP CEP19 CYLD FLII LXN MAGEF1 MAPRE2 MAPRE3 POLK POLR1C RNF114 RNF4 TNFRSF1B TRAF1 TRAF2 TRIM23 TRIM41 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2K UBE2U UBE2Z UBOX5 USP2	6 interacting genes: MDFI MMS19 NSMCE1 PHF7 TRAIP TRIM27
Entrez ID		10293	64110
HPRD ID		05811	14348
Ensembl ID		ENSG00000183763	ENSG00000177383
Uniprot IDs		Q9BWF2	Q9HAY2
PDB IDs		4ZTD
Enriched GO Terms of Interacting Partners?
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