CARD10 and METTL17

Data Source:
BioGRID (two hybrid)

		CARD10	METTL17
Description		caspase recruitment domain family member 10	methyltransferase like 17
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm CBM Complex	Nucleoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Signaling Receptor Complex Adaptor Activity CARD Domain Binding	Protein Binding Methyltransferase Activity S-adenosyl-L-methionine Binding
	Biological Process	Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Apoptotic Process Protein-containing Complex Assembly Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Protein Localization To Nucleus	Translation Methylation Ribosomal Small Subunit Biogenesis
Pathways
Drugs
Diseases
GWAS		Autoimmune hepatitis type-1 ( 24768677) Low vWF levels ( 26486471) Optic disc area ( 25631615 31798171 28073927 21307088) Optic disc size ( 31809533) Refractive error ( 32231278) Vertical cup-disc ratio ( 25241763 28073927) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Degraded stimulus continuous performance test score ( 31596458)
Interacting Genes		105 interacting genes: ATXN7 BAHD1 BCL10 BCL6B C4orf45 C8orf48 CARD9 CATSPER1 CBX8 CCDC116 CCDC187 CDC37 CEP95 CHIC2 CNNM3 CWF19L2 CXCL16 CYSRT1 DHX57 DOCK2 DUSP26 FAM47B FOXD4L3 GADD45GIP1 GAS8 GFAP GIPC1 GPATCH2L GSE1 GSTP1 HBZ HOXB9 IKBKG IL16 JOSD1 KANK2 KDM1A KEAP1 KLHL12 KRT75 KRTAP10-8 KRTAP12-3 KRTAP26-1 KRTAP9-2 KRTAP9-3 LENG1 MAGOHB METTL17 MITD1 MYPOP NME7 OLIG3 PIBF1 PKP1 PNKP PRDM14 PRPF18 PRPF3 PRR35 PTCD1 PTGDS RIN1 SCNM1 SEMA3B SPATA18 TBC1D22B TBC1D26 TFAP2D TMEM43 TRIM27 TRIM41 USP54 UTP14C ZBTB26 ZFP1 ZNF10 ZNF12 ZNF165 ZNF180 ZNF202 ZNF223 ZNF239 ZNF250 ZNF285 ZNF286A ZNF32 ZNF329 ZNF366 ZNF414 ZNF415 ZNF439 ZNF440 ZNF524 ZNF552 ZNF559 ZNF564 ZNF575 ZNF581 ZNF587 ZNF613 ZNF670 ZNF775 ZNF80 ZNF837 ZSCAN25	21 interacting genes: ATXN1 ATXN1L CALCOCO2 CARD10 CBY2 CEP70 KRT34 KRT40 MAPK6 MDFI MEOX2 MID2 MTUS2 NUDT16L1 NUTM1 PNMA1 SF3B4 TFIP11 TRAF1 TRIP6 VCP
Entrez ID		29775	64745
HPRD ID		06233	13379
Ensembl ID		ENSG00000100065	ENSG00000165792
Uniprot IDs		Q9BWT7	A0A0S2Z5L8 Q9H7H0
PDB IDs
Enriched GO Terms of Interacting Partners?
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