BLOC1S5 and HSBP1

Data Source:
BioGRID (two hybrid)

		BLOC1S5	HSBP1
Description		biogenesis of lysosomal organelles complex 1 subunit 5	heat shock factor binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Transport Vesicle BLOC-1 Complex Axon Cytoplasm	Nucleus Nucleoplasm Cytosol Cytoskeleton
	Molecular Function	Protein Binding	Transcription Corepressor Activity Protein Binding Identical Protein Binding
	Biological Process	Anterograde Axonal Transport Neuron Projection Development Melanosome Transport Melanosome Organization Endosome To Melanosome Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Endodermal Cell Differentiation Cellular Heat Acclimation Regulation Of Cellular Response To Heat
Pathways			HSF1 activation Attenuation phase HSF1-dependent transactivation
Drugs
Diseases
GWAS		Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)	Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		15 interacting genes: ABI2 ABI3 APP BLOC1S1 BLOC1S2 BLOC1S4 DTNBP1 HSBP1 LRRK1 OIP5 PBX2 PKNOX1 SMARCD1 SNAPIN TSNAX	21 interacting genes: BLOC1S5 BRK1 CCHCR1 CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPP7 NOTCH2NLA SDCBP SDCBP2 WASHC1 WASHC3 ZBTB25
Entrez ID		63915	3281
HPRD ID		06289	05185
Ensembl ID		ENSG00000188428	ENSG00000230989
Uniprot IDs		A0A0A0MTN6 Q8TDH9	O75506
PDB IDs			3CI9
Enriched GO Terms of Interacting Partners?
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