HSBP1 and BLOC1S5

Data Source:
BioGRID (two hybrid)

		HSBP1	BLOC1S5
Description		heat shock factor binding protein 1	biogenesis of lysosomal organelles complex 1 subunit 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cytoskeleton	Transport Vesicle BLOC-1 Complex Axon Cytoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Endodermal Cell Differentiation Cellular Heat Acclimation Regulation Of Cellular Response To Heat	Anterograde Axonal Transport Neuron Projection Development Melanosome Transport Melanosome Organization Endosome To Melanosome Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation
Pathways		HSF1 activation Attenuation phase HSF1-dependent transactivation
Drugs
Diseases
GWAS		Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)	Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		21 interacting genes: BLOC1S5 BRK1 CCHCR1 CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPP7 NOTCH2NLA SDCBP SDCBP2 WASHC1 WASHC3 ZBTB25	15 interacting genes: ABI2 ABI3 APP BLOC1S1 BLOC1S2 BLOC1S4 DTNBP1 HSBP1 LRRK1 OIP5 PBX2 PKNOX1 SMARCD1 SNAPIN TSNAX
Entrez ID		3281	63915
HPRD ID		05185	06289
Ensembl ID		ENSG00000230989	ENSG00000188428
Uniprot IDs		O75506	A0A0A0MTN6 Q8TDH9
PDB IDs		3CI9
Enriched GO Terms of Interacting Partners?
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