HSBP1 and ZBTB25

Data Source:
BioGRID (two hybrid)

		HSBP1	ZBTB25
Description		heat shock factor binding protein 1	zinc finger and BTB domain containing 25
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cytoskeleton	Nucleoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Endodermal Cell Differentiation Cellular Heat Acclimation Regulation Of Cellular Response To Heat	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		HSF1 activation Attenuation phase HSF1-dependent transactivation
Drugs
Diseases
GWAS		Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)	Heel bone mineral density ( 30598549) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 32888494 27863252)
Interacting Genes		21 interacting genes: BLOC1S5 BRK1 CCHCR1 CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPP7 NOTCH2NLA SDCBP SDCBP2 WASHC1 WASHC3 ZBTB25	34 interacting genes: APIP COIL CRACR2B CYP2J2 CYSRT1 DDIT3 FCGR3A FHL2 HCLS1 HOMEZ HSBP1 KCTD1 KCTD9 KRTAP10-8 KRTAP17-1 KXD1 LZTS2 MAPK9 MDFI PCBD1 PNMA5 SEPHS1 SORBS3 SSX3 SUMO2 TBC1D5 TNIP1 TRAF2 TRAF6 TSSK3 VCP VMAC ZBTB1 ZBTB2
Entrez ID		3281	7597
HPRD ID		05185	01926
Ensembl ID		ENSG00000230989	ENSG00000089775
Uniprot IDs		O75506	G3V2K3 P24278
PDB IDs		3CI9
Enriched GO Terms of Interacting Partners?
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