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DUSP21 and RGS2
Data Source:
BioGRID
(two hybrid)
DUSP21
RGS2
Description
dual specificity phosphatase 21
regulator of G protein signaling 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrial Matrix
Extrinsic Component Of Mitochondrial Inner Membrane
Nucleus
Nucleolus
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Cytoplasmic Side Of Plasma Membrane
Neuron Projection
Molecular Function
Protein Tyrosine Phosphatase Activity
Protein Binding
MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
Protein Serine Phosphatase Activity
Protein Threonine Phosphatase Activity
G-protein Alpha-subunit Binding
GTPase Activity
GTPase Activator Activity
Protein Binding
Calmodulin Binding
Beta-tubulin Binding
Biological Process
Inactivation Of MAPK Activity
Peptidyl-tyrosine Dephosphorylation
Response To Amphetamine
Cell Cycle
G Protein-coupled Receptor Signaling Pathway
Spermatogenesis
Brain Development
Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Phospholipase Activity
Negative Regulation Of Cardiac Muscle Hypertrophy
Positive Regulation Of Neuron Projection Development
Negative Regulation Of Translation
Ovulation
Negative Regulation Of MAP Kinase Activity
Positive Regulation Of GTPase Activity
Negative Regulation Of CAMP-mediated Signaling
Response To Ethanol
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Brown Fat Cell Differentiation
Relaxation Of Cardiac Muscle
Relaxation Of Vascular Associated Smooth Muscle
Maternal Process Involved In Female Pregnancy
Positive Regulation Of Cardiac Muscle Contraction
Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Negative Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Involved In Heart Process
Negative Regulation Of Glycine Import Across Plasma Membrane
Pathways
G alpha (q) signalling events
Drugs
Diseases
GWAS
Coronary artery calcification (
23870195
)
Response to quetiapine in schizophrenia (
29503163
)
Interacting Genes
33 interacting genes:
APP
ATP23
BPIFA1
CPNE7
CTBP2
EPHA3
EPHA5
ERBB3
ERBB4
EYA2
FAAP20
GET4
GORASP2
IGF1R
KLHL20
KRT33B
KRTAP11-1
MAP2K5
MYO15B
OIP5
POU4F3
PTK7
RFX6
RGS2
ROR1
ROR2
SUOX
TEX11
TOX3
TRAF1
UBQLN2
USP2
ZMAT1
61 interacting genes:
ADCY5
ADRA1A
ADRB2
ARFGAP1
BBS10
CALM1
CEP126
CHD3
CIAO1
CLTA
COMT
COPB1
COPB2
CRMP1
CTSB
DDR1
DUSP21
DYNLL1
EGFR
EIF3L
FZD5
GDE1
GIT1
GNA15
GNAI3
GNAQ
GNAS
HAUS5
HSPA8
IER3IP1
KLK8
LIG1
LRFN1
MARCHF6
METTL18
MON1A
MTUS2
NINL
NIPSNAP1
PPP1R9B
PRKCA
PRKCB
PRKCG
PRKCSH
PRKG1
PRKN
RAB2A
RABAC1
RAP1B
REEP5
RIN3
SCN5A
TSPAN15
TUBB2B
UBC
VPS29
WDR74
XRCC6
ZBTB48
ZNF579
ZYX
Entrez ID
63904
5997
HPRD ID
06494
02917
Ensembl ID
ENSG00000189037
ENSG00000116741
Uniprot IDs
Q9H596
A0A024R939
P41220
PDB IDs
2AF0
2V4Z
4EKC
4EKD
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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