RGS2 and CIAO1

Data Source:
BioGRID (two hybrid)

		RGS2	CIAO1
Description		regulator of G protein signaling 2	cytosolic iron-sulfur assembly component 1
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Mitochondrion Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Neuron Projection	Cytoplasm MMXD Complex CIA Complex
	Molecular Function	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Protein Binding Calmodulin Binding Beta-tubulin Binding	Protein Binding
	Biological Process	Response To Amphetamine Cell Cycle G Protein-coupled Receptor Signaling Pathway Spermatogenesis Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Phospholipase Activity Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Neuron Projection Development Negative Regulation Of Translation Ovulation Negative Regulation Of MAP Kinase Activity Positive Regulation Of GTPase Activity Negative Regulation Of CAMP-mediated Signaling Response To Ethanol Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Brown Fat Cell Differentiation Relaxation Of Cardiac Muscle Relaxation Of Vascular Associated Smooth Muscle Maternal Process Involved In Female Pregnancy Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of Glycine Import Across Plasma Membrane	Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Positive Regulation Of Cell Population Proliferation Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer
Pathways		G alpha (q) signalling events	Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS		Coronary artery calcification ( 23870195) Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes		61 interacting genes: ADCY5 ADRA1A ADRB2 ARFGAP1 BBS10 CALM1 CEP126 CHD3 CIAO1 CLTA COMT COPB1 COPB2 CRMP1 CTSB DDR1 DUSP21 DYNLL1 EGFR EIF3L FZD5 GDE1 GIT1 GNA15 GNAI3 GNAQ GNAS HAUS5 HSPA8 IER3IP1 KLK8 LIG1 LRFN1 MARCHF6 METTL18 MON1A MTUS2 NINL NIPSNAP1 PPP1R9B PRKCA PRKCB PRKCG PRKCSH PRKG1 PRKN RAB2A RABAC1 RAP1B REEP5 RIN3 SCN5A TSPAN15 TUBB2B UBC VPS29 WDR74 XRCC6 ZBTB48 ZNF579 ZYX	18 interacting genes: APP CCDC7 CIAO2A CIAO2B GOLM1 HAUS3 MEOX1 MEOX2 PGRMC1 RGS2 SF1 SHISA6 SLC4A7 SRPK1 TCP10L TOP3B URI1 WT1
Entrez ID		5997	9391
HPRD ID		02917	16057
Ensembl ID		ENSG00000116741	ENSG00000144021
Uniprot IDs		A0A024R939 P41220	O76071
PDB IDs		2AF0 2V4Z 4EKC 4EKD	3FM0
Enriched GO Terms of Interacting Partners?
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