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CCL19 and ATP6V0B
Data Source:
BioGRID
(affinity chromatography technology)
CCL19
ATP6V0B
Description
C-C motif chemokine ligand 19
ATPase H+ transporting V0 subunit b
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Vacuolar Membrane
Endosome Membrane
Integral Component Of Membrane
Phagocytic Vesicle Membrane
Proton-transporting V-type ATPase, V0 Domain
Molecular Function
Protein Binding
Chemokine Activity
CCR7 Chemokine Receptor Binding
CCR10 Chemokine Receptor Binding
Chemokine Receptor Binding
CCR Chemokine Receptor Binding
Transporter Activity
Protein Binding
Proton-transporting ATPase Activity, Rotational Mechanism
Biological Process
Establishment Of T Cell Polarity
Immunological Synapse Formation
Dendritic Cell Chemotaxis
Myeloid Dendritic Cell Chemotaxis
Monocyte Chemotaxis
Positive Regulation Of Dendritic Cell Antigen Processing And Presentation
Cellular Calcium Ion Homeostasis
Inflammatory Response
Immune Response
Cell Communication
G Protein-coupled Receptor Signaling Pathway
Activation Of JUN Kinase Activity
Response To Virus
Positive Regulation Of Glycoprotein Biosynthetic Process
Cytokine-mediated Signaling Pathway
Neutrophil Chemotaxis
T Cell Costimulation
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Tumor Necrosis Factor Production
Response To Prostaglandin E
Positive Regulation Of T Cell Proliferation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of GTPase Activity
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Positive Regulation Of T-helper 1 Cell Differentiation
Positive Regulation Of Endocytosis
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
Lymphocyte Chemotaxis
Positive Regulation Of Receptor-mediated Endocytosis
Cell Maturation
Positive Regulation Of Chemotaxis
Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Protein Kinase B Signaling
Regulation Of Cell Projection Assembly
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Response To Nitric Oxide
Positive Regulation Of Neutrophil Chemotaxis
Mature Conventional Dendritic Cell Differentiation
Cellular Response To Virus
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Cell Motility
Positive Regulation Of Dendritic Cell Dendrite Assembly
Negative Regulation Of Dendritic Cell Apoptotic Process
Insulin Receptor Signaling Pathway
Regulation Of Macroautophagy
Transferrin Transport
Ion Transmembrane Transport
Phagosome Acidification
Proton Transmembrane Transport
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
ROS and RNS production in phagocytes
Insulin receptor recycling
Transferrin endocytosis and recycling
Amino acids regulate mTORC1
Ion channel transport
Drugs
Tiludronic acid
Diseases
GWAS
Metabolite levels (
23823483
)
Rheumatoid arthritis (
30423114
24390342
)
Autism spectrum disorder or schizophrenia (
28540026
)
Interacting Genes
8 interacting genes:
ACKR2
ACKR4
CCL22
CCR10
CCR7
CXCL13
MEOX2
PF4V1
28 interacting genes:
ADGRG3
ADRB2
APOD
COL4A5
EMP1
FAM210B
FAS
GJA8
GPR42
GPR61
INSIG2
IRAK3
KLRC1
MFF
MIP
MS4A3
MTNR1B
NRM
SLC10A1
SLC2A5
SNTA1
SPACA1
STOM
TM4SF19
TMEM242
VMA21
YWHAE
YWHAG
Entrez ID
6363
533
HPRD ID
03750
04759
Ensembl ID
ENSG00000172724
ENSG00000117410
Uniprot IDs
Q6IBD6
Q99731
E9PNL3
Q99437
PDB IDs
2MP1
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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