CCL17 and CCL26

Data Source:
BioGRID (pull down)

		CCL17	CCL26
Description		C-C motif chemokine ligand 17	C-C motif chemokine ligand 26
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GO Annotations	Cellular Component	Extracellular Space	Extracellular Space
	Molecular Function	Signaling Receptor Binding Protein Binding Chemokine Activity CCR4 Chemokine Receptor Binding CCR Chemokine Receptor Binding	Protein Binding Chemokine Activity CCR3 Chemokine Receptor Binding Receptor Ligand Activity CCR Chemokine Receptor Binding
	Biological Process	Monocyte Chemotaxis Chemotaxis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Multicellular Organism Development Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation Of Myoblast Differentiation Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Positive Regulation Of Endothelial Cell Proliferation Monocyte Chemotaxis Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Positive Regulation Of Cell Migration Neutrophil Chemotaxis Positive Regulation Of Actin Filament Polymerization Positive Regulation Of GTPase Activity Eosinophil Chemotaxis Lymphocyte Chemotaxis Positive Regulation Of Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways		Chemokine receptors bind chemokines
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269)	Carotid plaque burden ( 28282560) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
Interacting Genes		9 interacting genes: ACKR1 CCL21 CCL25 CCL26 CCL28 CCL5 CCR4 CCR8 VCAM1	24 interacting genes: APP C3orf52 CCL11 CCL13 CCL17 CCL2 CCL21 CCL28 CCL5 CCL8 CCR1 CCR3 CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL9 PAX6 PF4 PF4V1 PPBP XCL1 XCL2
Entrez ID		6361	10344
HPRD ID		03309	05262
Ensembl ID		ENSG00000102970	ENSG00000006606
Uniprot IDs		Q92583	Q9Y258
PDB IDs		1NR2 1NR4 5WK3	1G2S 1G2T
Enriched GO Terms of Interacting Partners?
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