CCL26 and CCL17

Data Source:
BioGRID (pull down)

		CCL26	CCL17
Description		C-C motif chemokine ligand 26	C-C motif chemokine ligand 17
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GO Annotations	Cellular Component	Extracellular Space	Extracellular Space
	Molecular Function	Protein Binding Chemokine Activity CCR3 Chemokine Receptor Binding Receptor Ligand Activity CCR Chemokine Receptor Binding	Signaling Receptor Binding Protein Binding Chemokine Activity CCR4 Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Monocyte Chemotaxis Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Positive Regulation Of Cell Migration Neutrophil Chemotaxis Positive Regulation Of Actin Filament Polymerization Positive Regulation Of GTPase Activity Eosinophil Chemotaxis Lymphocyte Chemotaxis Positive Regulation Of Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Monocyte Chemotaxis Chemotaxis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Multicellular Organism Development Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation Of Myoblast Differentiation Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways			Chemokine receptors bind chemokines
Drugs
Diseases
GWAS		Carotid plaque burden ( 28282560) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)	Blood protein levels ( 30072576 29875488 28240269)
Interacting Genes		24 interacting genes: APP C3orf52 CCL11 CCL13 CCL17 CCL2 CCL21 CCL28 CCL5 CCL8 CCR1 CCR3 CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL9 PAX6 PF4 PF4V1 PPBP XCL1 XCL2	9 interacting genes: ACKR1 CCL21 CCL25 CCL26 CCL28 CCL5 CCR4 CCR8 VCAM1
Entrez ID		10344	6361
HPRD ID		05262	03309
Ensembl ID		ENSG00000006606	ENSG00000102970
Uniprot IDs		Q9Y258	Q92583
PDB IDs		1G2S 1G2T	1NR2 1NR4 5WK3
Enriched GO Terms of Interacting Partners?
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