CCL26 and PF4V1

Data Source:
BioGRID (pull down)

		CCL26	PF4V1
Description		C-C motif chemokine ligand 26	platelet factor 4 variant 1
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GO Annotations	Cellular Component	Extracellular Space	Extracellular Space
	Molecular Function	Protein Binding Chemokine Activity CCR3 Chemokine Receptor Binding Receptor Ligand Activity CCR Chemokine Receptor Binding	Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Monocyte Chemotaxis Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Positive Regulation Of Cell Migration Neutrophil Chemotaxis Positive Regulation Of Actin Filament Polymerization Positive Regulation Of GTPase Activity Eosinophil Chemotaxis Lymphocyte Chemotaxis Positive Regulation Of Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Inflammatory Response Platelet Activation Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways			Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Carotid plaque burden ( 28282560) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)	Blood protein levels ( 29875488) Inflammatory bowel disease ( 23128233)
Interacting Genes		24 interacting genes: APP C3orf52 CCL11 CCL13 CCL17 CCL2 CCL21 CCL28 CCL5 CCL8 CCR1 CCR3 CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL9 PAX6 PF4 PF4V1 PPBP XCL1 XCL2	15 interacting genes: CCL11 CCL19 CCL21 CCL22 CCL25 CCL26 CCL27 CCL28 CCL4L1 CXCL10 CXCL11 CXCL12 CXCL13 XCL1 XCL2
Entrez ID		10344	5197
HPRD ID		05262	01427
Ensembl ID		ENSG00000006606	ENSG00000109272
Uniprot IDs		Q9Y258	P10720
PDB IDs		1G2S 1G2T	4HSV
Enriched GO Terms of Interacting Partners?
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