SAFB and SREK1

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		SAFB	SREK1
Description		scaffold attachment factor B	splicing regulatory glutamic acid and lysine rich protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Midbody	Nucleoplasm Spliceosomal Complex Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding Double-stranded DNA Binding RNA Binding Protein Binding Sequence-specific DNA Binding	RNA Binding Protein Binding
	Biological Process	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Intracellular Estrogen Receptor Signaling Pathway Regulation Of MRNA Processing	MRNA Processing RNA Splicing
Pathways		SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494)	Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)
Interacting Genes		28 interacting genes: ABHD16A CDC37 CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R MIR199A1 MIR363 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7D NCOR1 POLR2A SAFB2 SREK1 SRPK1 SRPK2 SRSF9 SUMO2 TAF15 TJP2	60 interacting genes: ARL6IP4 CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GPRASP2 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 PRPF40A RACK1 RBM10 RBM39 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B TXLNA YBX1 ZRANB2
Entrez ID		6294	140890
HPRD ID		04205	18043
Ensembl ID		ENSG00000160633	ENSG00000153914
Uniprot IDs		B7Z2F6 B7ZLP5 Q15424	Q8WXA9
PDB IDs
Enriched GO Terms of Interacting Partners?
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