RPL23A and IPO5

Data Source:
HPRD (in vitro)

		RPL23A	IPO5
Description		ribosomal protein L23a	importin 5
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Cytosolic Large Ribosomal Subunit Extracellular Exosome	Nucleus Nuclear Pore Nucleolus Cytoplasm Membrane
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding Cadherin Binding TORC2 Complex Binding	RNA Binding GTPase Inhibitor Activity Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Ribosomal Large Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Amino Acid Stimulus
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	vRNP Assembly
Drugs		(S)-3-phenyllactic acid Anisomycin Puromycin Artenimol
Diseases
GWAS		Total cholesterol levels ( 30275531)	Peripheral artery disease ( 26488411) Smooth-surface caries ( 24556642)
Interacting Genes		7 interacting genes: CTPS2 DUX4 IPO5 IPO7 NAP1L1 PTEN TNPO1	26 interacting genes: ACD BHLHB9 CAB39 CDC42 DPPA3 DTNBP1 H1-0 NUP153 NUP214 NUP62 NUP98 PTEN RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 SUMO2 TERF1 TINF2 WASL
Entrez ID		6147	3843
HPRD ID		15998	03597
Ensembl ID		ENSG00000198242	ENSG00000065150
Uniprot IDs		P62750	B3KWG6 O00410 Q9BVS9
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6SXO 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO	6XTE 6XU2
Enriched GO Terms of Interacting Partners?
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