IPO5 and DPPA3

Data Source:
HPRD (in vivo, in vitro)

		IPO5	DPPA3
Description		importin 5	developmental pluripotency associated 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleolus Cytoplasm Membrane	Female Pronucleus Male Pronucleus Nucleus Cytoplasm
	Molecular Function	RNA Binding GTPase Inhibitor Activity Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity	Protein Binding Methylated Histone Binding
	Biological Process	Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Amino Acid Stimulus	Chromatin Organization Protection Of DNA Demethylation Of Female Pronucleus Negative Regulation Of DNA Demethylation Regulation Of Genetic Imprinting
Pathways		vRNP Assembly
Drugs
Diseases
GWAS		Peripheral artery disease ( 26488411) Smooth-surface caries ( 24556642)	Borderline personality disorder ( 28632202) White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes		26 interacting genes: ACD BHLHB9 CAB39 CDC42 DPPA3 DTNBP1 H1-0 NUP153 NUP214 NUP62 NUP98 PTEN RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 SUMO2 TERF1 TINF2 WASL	14 interacting genes: DEPDC5 DYNLL1 DYNLL2 HAUS7 IPO5 KRT27 KRT76 NUP62 PLEKHG4 SERTAD3 SYCE1L TFIP11 TRIB3 ZNF618
Entrez ID		3843	359787
HPRD ID		03597	16331
Ensembl ID		ENSG00000065150	ENSG00000187569
Uniprot IDs		B3KWG6 O00410 Q9BVS9	Q6W0C5
PDB IDs		6XTE 6XU2
Enriched GO Terms of Interacting Partners?
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