IPO5 and NUP98

Data Source:
HPRD (in vivo, in vitro)

		IPO5	NUP98
Description		importin 5	nucleoporin 98 and 96 precursor
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GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleolus Cytoplasm Membrane	Kinetochore Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Nuclear Body Nuclear Pore Outer Ring Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Intracellular Membrane-bounded Organelle Host Cell Nuclear Pore Nuclear Basket Ribonucleoprotein Complex
	Molecular Function	RNA Binding GTPase Inhibitor Activity Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity	Transcription Coactivator Activity MRNA Binding Transporter Activity Protein Binding Nuclear Localization Sequence Binding Serine-type Peptidase Activity Structural Constituent Of Nuclear Pore Promoter-specific Chromatin Binding
	Biological Process	Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Amino Acid Stimulus	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Proteolysis Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Pore Organization Viral Process Protein Sumoylation Viral Transcription Positive Regulation Of Transcription, DNA-templated Positive Regulation Of MRNA Splicing, Via Spliceosome Nuclear Pore Complex Assembly Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways		vRNP Assembly
Drugs
Diseases
GWAS		Peripheral artery disease ( 26488411) Smooth-surface caries ( 24556642)	Malaria ( 31844061) Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736)
Interacting Genes		26 interacting genes: ACD BHLHB9 CAB39 CDC42 DPPA3 DTNBP1 H1-0 NUP153 NUP214 NUP62 NUP98 PTEN RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 SUMO2 TERF1 TINF2 WASL	19 interacting genes: APC CREBBP CSNK2A1 EP300 HDAC1 IPO5 KPNB1 NFX1 NUP133 NUP155 NUP62 NUP88 NXF1 RAE1 RCC1 SEC13 TNPO1 TNPO2 TPR
Entrez ID		3843	4928
HPRD ID		03597	03012
Ensembl ID		ENSG00000065150	ENSG00000110713
Uniprot IDs		B3KWG6 O00410 Q9BVS9	P52948
PDB IDs		6XTE 6XU2	1KO6 2Q5X 2Q5Y 3MMY 4OWR 5A9Q 6BZM
Enriched GO Terms of Interacting Partners?
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