RPL9 and PNMA2

Data Source:
BioGRID (two hybrid, two hybrid)

		RPL9	PNMA2
Description		ribosomal protein L9	PNMA family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit	Nucleolus
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Positive Regulation Of Apoptotic Process
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258)	Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		36 interacting genes: BACH2 BICDL2 CALCOCO2 CBY2 CCDC184 CEP76 CTTN DHPS DRAP1 DUX4 ESR1 FAM9B HMBOX1 HOMEZ KXD1 MOCS2 MTUS2 PNMA2 PPP1R27 PSTPIP1 RALY RPS3 SNRPF SORBS2 SREK1IP1 SRSF3 STAC3 TIFA TNFAIP8L1 TRIM37 UBALD1 USO1 VCP ZBTB14 ZBTB7B ZBTB8A	32 interacting genes: BYSL CBX8 CCDC33 CDC37 CNNM3 ENKD1 FAM161A GPATCH2L HAPLN2 INO80B LRR1 MISP MORF4L2 NTAQ1 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RTP5 SCNM1 SDCBP THAP7 TOP3B TTLL10 ZNF408 ZNF417 ZNF587 ZNF669 ZNF688 ZNF785
Entrez ID		6133	10687
HPRD ID		04732	04915
Ensembl ID		ENSG00000163682	ENSG00000240694
Uniprot IDs		P32969 Q53Z07	Q5U5Z3 Q9UL42
PDB IDs		2CQL 4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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