RPL9 and ZBTB14

Data Source:
BioGRID (two hybrid)

		RPL9	ZBTB14
Description		ribosomal protein L9	zinc finger and BTB domain containing 14
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Negative Regulation Of Transcription By RNA Polymerase II Kidney Development Heart Valve Development Cardiac Septum Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Coronary Vasculature Development
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258)	Cerebral amyloid deposition (PET imaging) ( 26252872)
Interacting Genes		36 interacting genes: BACH2 BICDL2 CALCOCO2 CBY2 CCDC184 CEP76 CTTN DHPS DRAP1 DUX4 ESR1 FAM9B HMBOX1 HOMEZ KXD1 MOCS2 MTUS2 PNMA2 PPP1R27 PSTPIP1 RALY RPS3 SNRPF SORBS2 SREK1IP1 SRSF3 STAC3 TIFA TNFAIP8L1 TRIM37 UBALD1 USO1 VCP ZBTB14 ZBTB7B ZBTB8A	50 interacting genes: AP1M1 ATP5PO ATRIP BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 PIN1 PNKP POLR2L PRMT1 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2
Entrez ID		6133	7541
HPRD ID		04732	03674
Ensembl ID		ENSG00000163682	ENSG00000198081
Uniprot IDs		P32969 Q53Z07	B2R850 O43829
PDB IDs		2CQL 4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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