ELOVL5 and SYNJ2BP

Data Source:
BioGRID (two hybrid)

		ELOVL5	SYNJ2BP
Description		ELOVL fatty acid elongase 5	synaptojanin 2 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane Dendrite Neuronal Cell Body Dendritic Tree	Mitochondrion Mitochondrial Outer Membrane Ionotropic Glutamate Receptor Complex Basolateral Plasma Membrane Cell Junction Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane
	Molecular Function	Protein Binding Fatty Acid Elongase Activity 3-oxo-arachidoyl-CoA Synthase Activity 3-oxo-cerotoyl-CoA Synthase Activity 3-oxo-lignoceronyl-CoA Synthase Activity Very-long-chain 3-ketoacyl-CoA Synthase Activity	Protein Binding
	Biological Process	Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Alpha-linolenic Acid Metabolic Process Very Long-chain Fatty Acid Biosynthetic Process Linoleic Acid Metabolic Process Positive Regulation Of Fatty Acid Biosynthetic Process	Negative Regulation Of Endothelial Cell Proliferation Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis
Pathways		Linoleic acid (LA) metabolism alpha-linolenic acid (ALA) metabolism Synthesis of very long-chain fatty acyl-CoAs
Drugs		alpha-Linolenic acid
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 26252872) Daytime sleep phenotypes ( 27126917) Familial squamous cell lung carcinoma ( 29924316) Glaucoma ( 20363506) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Monocyte count ( 32888494) Red cell distribution width ( 32888494) Survival in colorectal cancer (distant metastatic) ( 26586795)	Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		16 interacting genes: C2CD2L GOSR2 HMOX1 HMOX2 HTR4 IGFBP5 NINJ2 PLP2 SLC39A9 STX7 SYNJ2BP SYS1 THSD7A TMEM243 TSNARE1 UBC	33 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1
Entrez ID		60481	55333
HPRD ID		13268	15455
Ensembl ID		ENSG00000012660	ENSG00000213463
Uniprot IDs		A0A024RD35 A0A0A0MTI6 B3KWH9 Q9NYP7	A0A024R670 P57105
PDB IDs			2ENO 2JIK 2JIN
Enriched GO Terms of Interacting Partners?
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