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EDA2R and NKG7
Data Source:
BioGRID
(two hybrid)
EDA2R
NKG7
Description
ectodysplasin A2 receptor
natural killer cell granule protein 7
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Integral Component Of Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Molecular Function
Tumor Necrosis Factor-activated Receptor Activity
Protein Binding
Signaling Receptor Activity
Protein Binding
Biological Process
Multicellular Organism Development
Epidermis Development
Ectodermal Cell Differentiation
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of JNK Cascade
Positive Regulation Of NF-kappaB Transcription Factor Activity
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways
TNFs bind their physiological receptors
Drugs
Diseases
GWAS
Balding (
26926045
)
Male-pattern baldness (
27182965
22032556
28196072
)
Neutrophil count (
32888494
27863252
)
Neutrophil percentage of white cells (
32888494
)
Interacting Genes
16 interacting genes:
AGR3
ATP6V0C
C1QB
CASP8
CEBPE
EDA
FADD
GIMAP5
JAGN1
NKG7
PLP1
SGTA
STRIT1
TMEM262
TRAF3
TRAF6
45 interacting genes:
AGTRAP
AMIGO1
AQP6
ARL13B
ATP6AP2
BAMBI
CD53
CD79A
CLDN7
CLEC2D
CLEC4E
CLSTN3
CREB3
EBP
EDA2R
ERGIC3
FAM210B
FFAR2
FNDC9
GJA5
GORAB
GPX8
ISLR2
KLRC1
LHFPL5
LMNA
MFSD6
MGST3
MS4A3
MSR1
MUC1
OPRK1
PEX12
RAMP1
RNF24
SLC18A2
SLC30A8
STOM
STX1A
TLCD4
TMEM106C
TMEM130
TMEM139
TMEM80
TMEM88
Entrez ID
60401
4818
HPRD ID
02230
16188
Ensembl ID
ENSG00000131080
ENSG00000105374
Uniprot IDs
B2RBZ9
B4DQY6
Q9HAV5
Q16617
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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