RDH5 and RLBP1

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		RDH5	RLBP1
Description		retinol dehydrogenase 5	retinaldehyde binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Membrane Cell Body	Nucleoplasm Centrosome Cytosol Cell Body
	Molecular Function	Retinol Dehydrogenase Activity Protein Homodimerization Activity Androsterone Dehydrogenase Activity Androstan-3-alpha,17-beta-diol Dehydrogenase Activity	11-cis Retinal Binding Protein Binding Retinol Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Retinoid Metabolic Process Visual Perception Steroid Metabolic Process Retinol Metabolic Process Response To Stimulus	Retinoid Metabolic Process Vitamin A Metabolic Process Visual Perception Response To Stimulus
Pathways		Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) RA biosynthesis pathway	The retinoid cycle in cones (daylight vision) The retinoid cycle in cones (daylight vision) Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision)
Drugs		NADH Vitamin A
Diseases		Familial flecked retina syndrome, including: Doyne honeycomb degeneration of retina (DHRD); Basal laminar drusen (BLD); Fundus albipunctatus (FA); Retinitis punctata albescens (RPA); Bietti crystalline corneoretinal dystrophy (BCD)	Newfoundland rod-cone dystrophy (NFRCD) Familial flecked retina syndrome, including: Doyne honeycomb degeneration of retina (DHRD); Basal laminar drusen (BLD); Fundus albipunctatus (FA); Retinitis punctata albescens (RPA); Bietti crystalline corneoretinal dystrophy (BCD)
GWAS		Advanced age-related macular degeneration ( 26691988) High myopia ( 31816047) Macular thickness ( 30535121) Myopia ( 27182965) Refractive error ( 23396134) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Advanced age-related macular degeneration ( 28813576) Age-related macular degeneration (SNP x mitochondrial G12771A interaction) ( 28813576) Schizophrenia ( 28991256)
Interacting Genes		3 interacting genes: ORC4 RGR RLBP1	4 interacting genes: APP KLHL8 RDH5 SLC9A3R1
Entrez ID		5959	6017
HPRD ID		03370	01572
Ensembl ID		ENSG00000135437	ENSG00000140522
Uniprot IDs		A0A024RB18 Q92781	P12271
PDB IDs			1XGG 1XGH 3HX3 3HY5 4CIZ 4CJ6
Enriched GO Terms of Interacting Partners?
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