IFRD1 and RIT1

Data Source:
HPRD (two hybrid)

		IFRD1	RIT1
Description		interferon related developmental regulator 1	Ras like without CAAX 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Plasma Membrane
	Molecular Function		GTPase Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Myoblast Fate Determination	Signal Transduction Ras Protein Signal Transduction
Pathways			Signalling to p38 via RIT and RIN
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (age of onset) ( 22959728) Dental caries (decayed, missing and filled teeth) ( 31533690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mortality in heart failure ( 20400778) Osteoarthritis (hip) ( 23989986) Refractive error ( 32231278)	Birth weight ( 31043758) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Conduct disorder (maternal expressed emotions interaction) ( 18846501) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 28067908 23128233) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: CSNK2A1 HDAC2 HDAC4 KLHL41 MYOD1 RIT1	17 interacting genes: AFDN AP2A1 CUL3 IFRD1 KLHL12 LRIF1 LRRK2 LZTR1 PTN RALGDS RGL1 RGL3 RLF SMAD2 SMAD3 SMURF1 SRPK2
Entrez ID		3475	6016
HPRD ID		04612	10195
Ensembl ID		ENSG00000006652	ENSG00000143622
Uniprot IDs		A4D0U1 O00458	Q92963
PDB IDs			4KLZ
Enriched GO Terms of Interacting Partners?
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