RGS10 and GNRHR

Data Source:
HPRD (in vivo)

		RGS10	GNRHR
Description		regulator of G protein signaling 10	gonadotropin releasing hormone receptor
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GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Neuronal Cell Body Dendritic Spine Axon Terminus	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Protein Binding	G Protein-coupled Receptor Activity Gonadotropin-releasing Hormone Receptor Activity Peptide Binding
	Biological Process	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity	G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Cellular Response To Gonadotropin-releasing Hormone
Pathways		G alpha (i) signalling events G alpha (i) signalling events	Hormone ligand-binding receptors G alpha (q) signalling events
Drugs			Leuprolide Goserelin Cetrorelix Abarelix Gonadorelin Nafarelin Danazol Teverelix Sufugolix Degarelix Buserelin Ganirelix Histrelin Triptorelin Gestrinone Relugolix Elagolix
Diseases			Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Depressive symptoms (stressful life events interaction) ( 27529621) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Obstetric antiphospholipid syndrome ( 28424481)	Regular attendance at a pub or social club ( 29970889)
Interacting Genes		10 interacting genes: ADRB2 APP CALM1 GNAI1 GNAI3 GNAO1 GNAZ GNRHR PLEKHF2 PRKACA	5 interacting genes: GNRH1 GPAA1 RGS10 TMEM161A TSPAN7
Entrez ID		6001	2798
HPRD ID		04172	00732
Ensembl ID		ENSG00000148908	ENSG00000109163
Uniprot IDs		O43665	P30968
PDB IDs		2DLR 2I59 2IHB	7BR3
Enriched GO Terms of Interacting Partners?
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