GNRHR and GNRH1

Data Source:
HPRD (in vivo)

		GNRHR	GNRH1
Description		gonadotropin releasing hormone receptor	gonadotropin releasing hormone 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane	Extracellular Region Extracellular Space Mitochondrion Golgi-associated Vesicle Dendrite Perikaryon Axon Terminus Cytoplasmic Side Of Rough Endoplasmic Reticulum Membrane Neurosecretory Vesicle
	Molecular Function	G Protein-coupled Receptor Activity Gonadotropin-releasing Hormone Receptor Activity Peptide Binding	Hormone Activity Gonadotropin Hormone-releasing Hormone Activity Gonadotropin-releasing Hormone Receptor Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Cellular Response To Gonadotropin-releasing Hormone	Reproduction Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Multicellular Organism Development Female Pregnancy Aging Negative Regulation Of Cell Population Proliferation Regulation Of Gene Expression Male Sex Determination Response To Corticosteroid Response To Lipopolysaccharide Negative Regulation Of Immature T Cell Proliferation Response To Testosterone Response To Prostaglandin E Response To Potassium Ion Negative Regulation Of Apoptotic Process Estrous Cycle Response To Ethanol Response To Prolactin Regulation Of Ovarian Follicle Development Negative Regulation Of Neuron Migration
Pathways		Hormone ligand-binding receptors G alpha (q) signalling events	Hormone ligand-binding receptors G alpha (q) signalling events
Drugs		Leuprolide Goserelin Cetrorelix Abarelix Gonadorelin Nafarelin Danazol Teverelix Sufugolix Degarelix Buserelin Ganirelix Histrelin Triptorelin Gestrinone Relugolix Elagolix
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Regular attendance at a pub or social club ( 29970889)	Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Length of menstrual cycle ( 30202859) Menopause (age at onset) ( 29773799) Metabolite levels ( 23823483) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		5 interacting genes: GNRH1 GPAA1 RGS10 TMEM161A TSPAN7	2 interacting genes: GNRHR MEP1A
Entrez ID		2798	2796
HPRD ID		00732	08860
Ensembl ID		ENSG00000109163	ENSG00000147437
Uniprot IDs		P30968	P01148
PDB IDs		7BR3	4D5M
Enriched GO Terms of Interacting Partners?
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