GNRHR and RGS10

Data Source:
HPRD (in vivo)

		GNRHR	RGS10
Description		gonadotropin releasing hormone receptor	regulator of G protein signaling 10
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane	Nucleus Cytosol Plasma Membrane Neuronal Cell Body Dendritic Spine Axon Terminus
	Molecular Function	G Protein-coupled Receptor Activity Gonadotropin-releasing Hormone Receptor Activity Peptide Binding	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Cellular Response To Gonadotropin-releasing Hormone	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Hormone ligand-binding receptors G alpha (q) signalling events	G alpha (i) signalling events G alpha (i) signalling events
Drugs		Leuprolide Goserelin Cetrorelix Abarelix Gonadorelin Nafarelin Danazol Teverelix Sufugolix Degarelix Buserelin Ganirelix Histrelin Triptorelin Gestrinone Relugolix Elagolix
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Regular attendance at a pub or social club ( 29970889)	Depressive symptoms (stressful life events interaction) ( 27529621) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Obstetric antiphospholipid syndrome ( 28424481)
Interacting Genes		5 interacting genes: GNRH1 GPAA1 RGS10 TMEM161A TSPAN7	10 interacting genes: ADRB2 APP CALM1 GNAI1 GNAI3 GNAO1 GNAZ GNRHR PLEKHF2 PRKACA
Entrez ID		2798	6001
HPRD ID		00732	04172
Ensembl ID		ENSG00000109163	ENSG00000148908
Uniprot IDs		P30968	O43665
PDB IDs		7BR3	2DLR 2I59 2IHB
Enriched GO Terms of Interacting Partners?
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