RFX2 and ICAM3

Data Source:
BioGRID (affinity chromatography technology)

		RFX2	ICAM3
Description		regulatory factor X2	intercellular adhesion molecule 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Signaling Receptor Binding Integrin Binding Protein Binding
	Biological Process	Acrosome Assembly Regulation Of Transcription By RNA Polymerase II Spermatid Development Cilium Assembly	Stimulatory C-type Lectin Receptor Signaling Pathway Phagocytosis Cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response Cell-cell Adhesion
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions CD209 (DC-SIGN) signaling
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Mean platelet volume ( 32888494 27863252) Platelet distribution width ( 32888494)	Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)
Interacting Genes		10 interacting genes: C1orf94 EYA2 FOXJ1 FOXN4 MDFI NFKBID PIAS2 RFX1 RFX4 RFX6	20 interacting genes: APP BRICD5 CD209 CLDN19 CLDN4 CLEC4M EDDM3B EZR ITGAD ITGAL ITGB2 MSN NINJ2 PRKCQ SEC22A SFTPC SMCO4 SMIM1 TSPO ZBTB16
Entrez ID		5990	3385
HPRD ID		00824	00889
Ensembl ID		ENSG00000087903	ENSG00000076662
Uniprot IDs		P48378	A0A024R7C1 K7ERN2 P32942
PDB IDs			1T0P
Enriched GO Terms of Interacting Partners?
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