RFX2 and RFX4

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		RFX2	RFX4
Description		regulatory factor X2	regulatory factor X4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Acrosome Assembly Regulation Of Transcription By RNA Polymerase II Spermatid Development Cilium Assembly	Regulation Of Transcription By RNA Polymerase II Telencephalon Development Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Positive Regulation Of Transcription By RNA Polymerase II Cilium Assembly Regulation Of Protein Processing
Pathways
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Mean platelet volume ( 32888494 27863252) Platelet distribution width ( 32888494)	Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cognitive test performance ( 17903297) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heart rate ( 23583979) Morning person ( 30696823) Night sleep phenotypes ( 27126917) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Triglyceride levels ( 28334899)
Interacting Genes		10 interacting genes: C1orf94 EYA2 FOXJ1 FOXN4 MDFI NFKBID PIAS2 RFX1 RFX4 RFX6	3 interacting genes: ESR1 RFX2 RFX3
Entrez ID		5990	5992
HPRD ID		00824	04905
Ensembl ID		ENSG00000087903	ENSG00000111783
Uniprot IDs		P48378	Q33E94
PDB IDs
Enriched GO Terms of Interacting Partners?
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