ICAM3 and CLEC4M

Data Source:
HPRD (in vitro)

		ICAM3	CLEC4M
Description		intercellular adhesion molecule 3	C-type lectin domain family 4 member M
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Extracellular Region Cytoplasm Integral Component Of Plasma Membrane Membrane Host Cell
	Molecular Function	Signaling Receptor Binding Integrin Binding Protein Binding	Virus Receptor Activity Protein Binding Mannose Binding Carbohydrate Binding ICAM-3 Receptor Activity Signaling Receptor Activity Peptide Antigen Binding Virion Binding Metal Ion Binding Calcium-dependent Protein Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Phagocytosis Cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response Cell-cell Adhesion	Adaptive Immune Response Endocytosis Leukocyte Cell-cell Adhesion Cell-cell Recognition Modulation By Virus Of Host Process Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Innate Immune Response Viral Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions CD209 (DC-SIGN) signaling
Drugs
Diseases
GWAS		Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)	Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) vWF levels ( 30586737) White blood cell count ( 32888494)
Interacting Genes		20 interacting genes: APP BRICD5 CD209 CLDN19 CLDN4 CLEC4M EDDM3B EZR ITGAD ITGAL ITGB2 MSN NINJ2 PRKCQ SEC22A SFTPC SMCO4 SMIM1 TSPO ZBTB16	5 interacting genes: CD209 ICAM3 IFT20 ITGAM PLPP6
Entrez ID		3385	10332
HPRD ID		00889	12060
Ensembl ID		ENSG00000076662	ENSG00000104938
Uniprot IDs		A0A024R7C1 K7ERN2 P32942	B4E2Z5 H7BXU4 Q9H2X3
PDB IDs		1T0P	1K9J 1SL6 1XAR 1XPH 1Z0Y 3JQH
Enriched GO Terms of Interacting Partners?
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