ICAM3 and ITGAD

Data Source:
HPRD (in vitro)

		ICAM3	ITGAD
Description		intercellular adhesion molecule 3	integrin subunit alpha D
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Plasma Membrane Integrin Complex Cell Surface
	Molecular Function	Signaling Receptor Binding Integrin Binding Protein Binding	Metal Ion Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Phagocytosis Cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response Cell-cell Adhesion	Immune Response Integrin-mediated Signaling Pathway Extracellular Matrix Organization Heterotypic Cell-cell Adhesion
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions CD209 (DC-SIGN) signaling	Integrin cell surface interactions
Drugs
Diseases
GWAS		Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		20 interacting genes: APP BRICD5 CD209 CLDN19 CLDN4 CLEC4M EDDM3B EZR ITGAD ITGAL ITGB2 MSN NINJ2 PRKCQ SEC22A SFTPC SMCO4 SMIM1 TSPO ZBTB16	4 interacting genes: ICAM3 ITGB2 SHARPIN VCAM1
Entrez ID		3385	3681
HPRD ID		00889	11785
Ensembl ID		ENSG00000076662	ENSG00000156886
Uniprot IDs		A0A024R7C1 K7ERN2 P32942	Q13349 Q59H14
PDB IDs		1T0P
Enriched GO Terms of Interacting Partners?
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