CPNE2 and UBE2O

Data Source:
HPRD (two hybrid)

		CPNE2	UBE2O
Description		copine 2	ubiquitin conjugating enzyme E2 O
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body
	Molecular Function	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding	RNA Binding Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Cellular Response To Calcium Ion	Protein Monoubiquitination Negative Regulation Of Endopeptidase Activity Positive Regulation Of BMP Signaling Pathway Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Protein K63-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mitochondrial DNA levels ( 25240745) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		28 interacting genes: ACTB ANXA7 BCOR CDKN1A CT55 EFHC2 GBP7 IKBKG KATNBL1 LNX1 MEI4 MEOX2 MYCBP NCKIPSD PDCD6 PICK1 PPP5C RDX REL SKIL SORBS3 TCF4 TERF2IP THAP4 TRIM27 UBA3 UBE2M UBE2O	17 interacting genes: APPL1 BAP1 CPNE1 CPNE2 CPNE4 HEXIM1 ITCH MAF MDM2 PRKN RNF10 RNF31 SFMBT2 SHBG TRIM27 UBC UBE2D3
Entrez ID		221184	63893
HPRD ID		05015	10928
Ensembl ID		ENSG00000140848	ENSG00000175931
Uniprot IDs		Q96FN4	Q9C0C9
PDB IDs
Enriched GO Terms of Interacting Partners?
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