RAD23B and NGLY1

Data Source:
BioGRID (biochemical, affinity chromatography technology, two hybrid)
HPRD (in vitro)

		RAD23B	NGLY1
Description		RAD23 homolog B, nucleotide excision repair protein	N-glycanase 1
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GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytosol XPC Complex	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding	Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity Protein Binding Metal Ion Binding
	Biological Process	Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Duplex Unwinding Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Assembly Protein Folding Spermatogenesis Protein Deubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Global Genome Nucleotide-excision Repair Cellular Response To Interleukin-7	Protein Folding Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Glycoprotein Catabolic Process Protein Deglycosylation
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER	N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Drugs
Diseases
GWAS		Body mass index ( 20966902) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 21263130) Chronotype ( 30696823) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Prostate cancer ( 23023329)
Interacting Genes		30 interacting genes: ADRM1 ATXN3 CALM1 DBI DEAF1 HIP1 HMGB1 MKRN1 MLH1 MPG NGLY1 PAQR3 PAX3 PNMA5 POU6F2 PSMC2 PSMD4 PUF60 RPA1 RSC1A1 TAX1BP1 TDG UBA2 UBB UBC UBE3A UBQLN2 USP25 XPC ZFAND5	18 interacting genes: APP BICRAL FAF1 GUCD1 NPAS2 NSFL1C PAX5 PAX6 RAD23A RAD23B SRPK2 TCF12 TRAFD1 TRIM54 UBQLN1 UBXN2B VCP VMAC
Entrez ID		5887	55768
HPRD ID		06772	10118
Ensembl ID		ENSG00000119318	ENSG00000151092
Uniprot IDs		B7Z4W4 P54727	Q96IV0
PDB IDs		1P1A 1PVE 1UEL	2CCQ 2CM0
Enriched GO Terms of Interacting Partners?
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