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NGLY1 and RAD23A
Data Source:
BioGRID
(two hybrid)
NGLY1
RAD23A
Description
N-glycanase 1
RAD23 homolog A, nucleotide excision repair protein
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Proteasome Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Protein-containing Complex
Centriolar Satellite
Intracellular Membrane-bounded Organelle
Molecular Function
Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity
Protein Binding
Metal Ion Binding
Damaged DNA Binding
Single-stranded DNA Binding
Protein Binding
Kinase Binding
Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Binding
Proteasome Binding
Ubiquitin-specific Protease Binding
Biological Process
Protein Folding
Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins
Glycoprotein Catabolic Process
Protein Deglycosylation
Nucleotide-excision Repair
Viral Process
Protein Deubiquitination
Protein Destabilization
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Viral Genome Replication
Positive Regulation Of Cell Cycle
Pathways
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Josephin domain DUBs
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS
Clozapine-induced agranulocytosis (
25187353
)
Interacting Genes
18 interacting genes:
APP
BICRAL
FAF1
GUCD1
NPAS2
NSFL1C
PAX5
PAX6
RAD23A
RAD23B
SRPK2
TCF12
TRAFD1
TRIM54
UBQLN1
UBXN2B
VCP
VMAC
76 interacting genes:
A2M
ADRM1
ANKRD40
ATXN3
ATXN7
CCNA2
CDC37
CHEK1
CNTROB
CREBBP
DAZAP2
DBI
ECSIT
EP300
EWSR1
FILIP1
GTF2H1
HSPB1
IFIT3
IFIT5
KRTAP12-2
LOXL4
MAP3K1
MAST1
MDM2
MINDY3
MKRN1
MPG
NEDD8
NGLY1
NUTM2F
PDE6D
PHAX
PI4K2A
PRKN
PSEN1
PSMC5
PSMD4
RABGEF1
REL
RNF115
RNF32
RNF41
RPN1
RPS27A
SH3RF1
SMURF1
SQSTM1
TNFAIP3
TRAF2
TRAF3
TRAF5
TRAF6
TRIM39
TRIM50
TRIM54
TRIM55
TRIM8
TRIP6
UBA52
UBB
UBC
UBE3A
UBE4B
UBL7
UBQLN2
UBQLN4
UBXN1
UIMC1
USP25
VAV2
XPC
ZBTB26
ZBTB44
ZBTB8A
ZFAND6
Entrez ID
55768
5886
HPRD ID
10118
07191
Ensembl ID
ENSG00000151092
ENSG00000179262
Uniprot IDs
Q96IV0
A0A024R7G8
A8K1J3
P54725
PDB IDs
2CCQ
2CM0
1DV0
1F4I
1IFY
1OQY
1P98
1P9D
1QZE
1TP4
1ZO6
2WYQ
5XBO
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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