RAB5B and SUN2

Data Source:
BioGRID (two hybrid)

		RAB5B	SUN2
Description		RAB5B, member RAS oncogene family	Sad1 and UNC84 domain containing 2
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GO Annotations	Cellular Component	Endosome Early Endosome Plasma Membrane Endomembrane System Membrane Endocytic Vesicle Secretory Granule Membrane Early Endosome Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nuclear Envelope Integral Component Of Nuclear Inner Membrane Endosome Membrane Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding	Protein Binding Lamin Binding Microtubule Binding Identical Protein Binding Protein-membrane Adaptor Activity Cytoskeleton-nuclear Membrane Anchor Activity
	Biological Process	Intracellular Protein Transport Endocytosis Endosome Organization Antigen Processing And Presentation Regulation Of Endocytosis Neutrophil Degranulation Plasma Membrane To Endosome Transport	Nuclear Envelope Organization Mitotic Spindle Organization Nuclear Migration Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Cell Migration Nuclear Migration Along Microfilament Meiotic Cell Cycle Centrosome Localization Nuclear Matrix Anchoring At Nuclear Membrane
Pathways		Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Meiotic synapsis
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 31959851 30929738 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) FEV1 ( 30804560) Gastroesophageal reflux disease ( 31527586) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 31928498) Lung function (FEV1) ( 30061609) Lung function (FEV1/FVC) ( 30804560) Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease) ( 31015401) Polycystic ovary syndrome ( 22885925 30566500) Refractive error ( 32231278) Sum eosinophil basophil counts ( 27863252) Type 1 diabetes ( 18198356) Vitiligo ( 22951725)	Heel bone mineral density ( 28869591) Prostate cancer ( 31562322) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		16 interacting genes: APOA5 CDK1 CHM EEA1 GLP1R PIK3CB RABAC1 REEP5 RIN1 RIN2 RIN3 SGSM3 SUN2 TBC1D15 TBC1D17 TFRC	4 interacting genes: HGS NRM RAB5B RPS20
Entrez ID		5869	25777
HPRD ID		01544	15611
Ensembl ID		ENSG00000111540	ENSG00000100242
Uniprot IDs		A0A024RB09 P61020	A0A024R1P7 B4E2A6 Q9UH99
PDB IDs		2HEI	3UNP 4DXR 4DXS 4DXT 4FI9
Enriched GO Terms of Interacting Partners?
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