ZNF462 and TULP3

Data Source:
BioGRID (two hybrid)

		ZNF462	TULP3
Description		zinc finger protein 462	TUB like protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Nucleus Nucleoplasm Nucleolus Plasma Membrane Cilium Axoneme Ciliary Base 9+0 Non-motile Cilium
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	G Protein-coupled Receptor Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Enzyme Binding Phosphatidylinositol Binding Protein-containing Complex Binding Intraciliary Transport Particle A Binding
	Biological Process	Chromatin Organization Regulation Of Gene Expression Negative Regulation Of DNA Binding Positive Regulation Of Transcription By RNA Polymerase II	Neural Tube Closure Regulation Of Transcription, DNA-templated G Protein-coupled Receptor Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Anterior/posterior Pattern Specification Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Central Nervous System Neuron Differentiation Embryonic Camera-type Eye Development Embryonic Digit Morphogenesis Negative Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Bone Development Bronchus Morphogenesis Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Protein Localization To Cilium Ganglion Development Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Pathways			Hedgehog 'off' state
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) ( 24025145) Age at voice drop ( 27182965) Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30679032) Atrial fibrillation ( 29892015) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cognitive decline rate in late mild cognitive impairment ( 26252872) Cutaneous malignant melanoma ( 26237428) Diastolic blood pressure ( 30224653) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Emphysema imaging phenotypes ( 26030696) Height ( 28552196 20881960 31562340 18391951) Lung function (FEV1/FVC) ( 30061609) Male-pattern baldness ( 28196072) Menarche (age at onset) ( 19448620 27182965) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Red blood cell count ( 32888494) Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for body mass index ( 28448500)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		3 interacting genes: EHMT2 FBXO7 TULP3	63 interacting genes: ACTN2 AKAP9 ANKRD1 ANKRD54 ARHGAP21 ARMCX2 ATP2A1 BACH2 BOC BRMS1L BTBD1 CCNB1 CHD2 CLIP4 DNTTIP2 DROSHA DST ESRRG GPATCH2L GSE1 HSF2BP KIF3A KLF10 KRTAP10-1 KRTAP10-5 KRTAP10-7 MAGEA6 MAP3K5 MBTD1 MGA MORF4L1 MYBPC2 MYH3 MYH7 MYO18B NCOR1 NFE2L1 NOSTRIN NRIP1 PAF1 PCGF6 PDE4DIP PHAX PRKAR1A PSTPIP1 RCOR3 RIOK3 RNF10 ROPN1 RYR1 SLAIN2 SPTB SRP72 TNNT1 TNNT3 WNK1 ZFAT ZNF160 ZNF462 ZNF619 ZNF793 ZNF835 ZSCAN23
Entrez ID		58499	7289
HPRD ID		10333	05292
Ensembl ID		ENSG00000148143	ENSG00000078246
Uniprot IDs		Q63HJ5 Q96JM2	B7Z1E7 O75386
PDB IDs		1X6F
Enriched GO Terms of Interacting Partners?
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