ZNF77 and RUSC1

Data Source:
BioGRID (two hybrid)

		ZNF77	RUSC1
Description		zinc finger protein 77	RUN and SH3 domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Early Endosome Golgi Apparatus Cytosol Microtubule Postsynaptic Density Microtubule Cytoskeleton Cytoplasmic Vesicle
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Molecular_function Protein Binding Metal Ion Binding	Actin Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Biological_process	Protein Polyubiquitination
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Chronic kidney disease ( 30226566) Coronary artery disease ( 30402224) Daytime sleep phenotypes ( 27126917) Ischemic stroke ( 29930801) Myocardial infarction ( 30226566)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		7 interacting genes: FTO MBD3L1 METTL27 NICN1 PRDX3 RSPO4 RUSC1	92 interacting genes: ABHD11 ABHD5 ABI2 AKAP8L ANKS1A APP ATP6V0D2 BPIFA1 C1orf109 CCDC120 CCDC57 CCHCR1 CCNC CDKN2B CMTM6 CREM CRYBA2 CTAG1A CTAG1B DMRT3 DOK6 DTX2 DVL2 EXOC8 EXOSC8 FAM9B FNDC3B GCM2 HMG20A HNRNPF INSC KCTD9 KRTAP19-1 KRTAP19-5 KRTAP6-2 KRTAP8-1 LIMS3 LIMS4 LMO2 MAGEA3 MAGEA6 MAGED1 MED25 MEIS2 MISP MOAP1 MORN3 MYOZ3 N4BP3 NICN1 NTAQ1 NTRK1 NUDT22 OIP5 P4HA3 PFDN5 PIK3R3 PLA2G6 PM20D2 PNMA1 POLR1C PRDM14 PRR35 RBPMS SMARCB1 SMYD1 SOHLH1 SPAG8 STUB1 SUOX TBC1D25 TCHP TEKT4 TENT5B TLE5 TRAPPC6A TRIM55 TRIM63 TRIM73 TSSK3 TTC19 TTC7B UFSP1 VGLL3 WWOX WWP2 ZIC1 ZMYND12 ZNF34 ZNF620 ZNF765 ZNF77
Entrez ID		58492	23623
HPRD ID		08936	10206
Ensembl ID		ENSG00000175691	ENSG00000160753
Uniprot IDs		Q15935	B4DQB8 Q9BVN2
PDB IDs			4GIW
Enriched GO Terms of Interacting Partners?
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