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RPRD1B and PIP4K2B
Data Source:
BioGRID
(two hybrid)
RPRD1B
PIP4K2B
Description
regulation of nuclear pre-mRNA domain containing 1B
phosphatidylinositol-5-phosphate 4-kinase type 2 beta
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
RNA Polymerase II, Holoenzyme
Nucleus
Nucleoplasm
Autophagosome
Endoplasmic Reticulum Membrane
Cytosol
Plasma Membrane
Molecular Function
RNA Polymerase II Complex Binding
Protein Binding
Identical Protein Binding
Protein Binding
ATP Binding
GTP Binding
1-phosphatidylinositol-4-phosphate 5-kinase Activity
1-phosphatidylinositol-5-phosphate 4-kinase Activity
Protein Homodimerization Activity
Biological Process
Positive Regulation Of Cell Population Proliferation
Regulation Of Cell Cycle Process
MRNA 3'-end Processing
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Dephosphorylation Of RNA Polymerase II C-terminal Domain
Phospholipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
Cell Surface Receptor Signaling Pathway
Regulation Of Autophagy
Regulation Of Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of Insulin Receptor Signaling Pathway
Phosphatidylinositol Phosphorylation
Autophagosome-lysosome Fusion
Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process
Positive Regulation Of Autophagosome Assembly
Pathways
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
Synthesis of PIPs at the plasma membrane
PI5P Regulates TP53 Acetylation
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Synthesis of PIPs in the nucleus
Drugs
Fostamatinib
Diseases
GWAS
Height (
28552196
20881960
31562340
)
Interacting Genes
19 interacting genes:
BIN3
CDCA8
DDIT4L
HMG20A
HOXC4
NUTF2
PFDN6
PIP4K2B
PSMB1
RASSF3
RPRD1A
SPG21
STEEP1
TERF2
TNPO2
TUBGCP4
UBE2I
VAX1
VPS37C
17 interacting genes:
BTK
CDCA7L
CLK1
CSNK2A1
HMBOX1
HSPB7
INO80B
KYNU
MLH1
PRPF3
PSMB1
RPRD1B
TNFRSF1A
TRIM55
TRIM63
UBQLN4
ZNF131
Entrez ID
58490
8396
HPRD ID
08513
04463
Ensembl ID
ENSG00000101413
ENSG00000276293
Uniprot IDs
Q9NQG5
P78356
PDB IDs
4FLA
4FU3
4HFG
4NAD
4Q94
4Q96
1BO1
3WZZ
3X01
3X02
3X03
3X04
3X05
3X06
3X07
3X08
3X09
3X0A
3X0B
3X0C
6K4G
6K4H
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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