RPRD1B and CDCA8

Data Source:
BioGRID (two hybrid)

		RPRD1B	CDCA8
Description		regulation of nuclear pre-mRNA domain containing 1B	cell division cycle associated 8
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GO Annotations	Cellular Component	Nucleus Nucleoplasm RNA Polymerase II, Holoenzyme	Chromosome, Centromeric Region Nucleoplasm Nucleolus Cytosol Chromocenter Midbody Chromosome Passenger Complex Protein-containing Complex Intercellular Bridge Spindle Midzone
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Process MRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Dephosphorylation Of RNA Polymerase II C-terminal Domain	Mitotic Sister Chromatid Segregation Mitotic Metaphase Plate Congression Chromosome Organization Cell Division
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		19 interacting genes: BIN3 CDCA8 DDIT4L HMG20A HOXC4 NUTF2 PFDN6 PIP4K2B PSMB1 RASSF3 RPRD1A SPG21 STEEP1 TERF2 TNPO2 TUBGCP4 UBE2I VAX1 VPS37C	26 interacting genes: AURKB BIRC5 EMILIN1 FBXO17 GYS1 H3C14 HLA-DRB3 HMBOX1 INCENP MAPKAPK5 NEK3 NKAPD1 NTAQ1 PIAS2 PIH1D2 RANBP2 RPRD1B SENP3 SET SGO1 SGO2 SNAPC5 SPANXN2 TTK UBE2I ZNF277
Entrez ID		58490	55143
HPRD ID		08513	13017
Ensembl ID		ENSG00000101413	ENSG00000134690
Uniprot IDs		Q9NQG5	Q53HL2
PDB IDs		4FLA 4FU3 4HFG 4NAD 4Q94 4Q96	2KDD 2QFA 2RAW 2RAX 6YIE 6YIF 6YIH
Enriched GO Terms of Interacting Partners?
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