CDCA8 and RPRD1B

Data Source:
BioGRID (two hybrid)

		CDCA8	RPRD1B
Description		cell division cycle associated 8	regulation of nuclear pre-mRNA domain containing 1B
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Nucleoplasm Nucleolus Cytosol Chromocenter Midbody Chromosome Passenger Complex Protein-containing Complex Intercellular Bridge Spindle Midzone	Nucleus Nucleoplasm RNA Polymerase II, Holoenzyme
	Molecular Function	Protein Binding	RNA Polymerase II Complex Binding Protein Binding Identical Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Metaphase Plate Congression Chromosome Organization Cell Division	Positive Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Process MRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Dephosphorylation Of RNA Polymerase II C-terminal Domain
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		26 interacting genes: AURKB BIRC5 EMILIN1 FBXO17 GYS1 H3C14 HLA-DRB3 HMBOX1 INCENP MAPKAPK5 NEK3 NKAPD1 NTAQ1 PIAS2 PIH1D2 RANBP2 RPRD1B SENP3 SET SGO1 SGO2 SNAPC5 SPANXN2 TTK UBE2I ZNF277	19 interacting genes: BIN3 CDCA8 DDIT4L HMG20A HOXC4 NUTF2 PFDN6 PIP4K2B PSMB1 RASSF3 RPRD1A SPG21 STEEP1 TERF2 TNPO2 TUBGCP4 UBE2I VAX1 VPS37C
Entrez ID		55143	58490
HPRD ID		13017	08513
Ensembl ID		ENSG00000134690	ENSG00000101413
Uniprot IDs		Q53HL2	Q9NQG5
PDB IDs		2KDD 2QFA 2RAW 2RAX 6YIE 6YIF 6YIH	4FLA 4FU3 4HFG 4NAD 4Q94 4Q96
Enriched GO Terms of Interacting Partners?
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