BBS2 and KCNK17

Data Source:
BioGRID (proximity labelling technology)

		BBS2	KCNK17
Description		Bardet-Biedl syndrome 2	potassium two pore domain channel subfamily K member 17
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Microvillus Membrane Motile Cilium Stereocilium BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding	Voltage-gated Ion Channel Activity Potassium Channel Activity Potassium Ion Leak Channel Activity
	Biological Process	Sperm Axoneme Assembly Visual Perception Protein Localization Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Multicellular Organism Growth Vasodilation Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cartilage Development Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly	Potassium Ion Transport Stabilization Of Membrane Potential Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		BBSome-mediated cargo-targeting to cilium	TWIK-related alkaline pH activated K+ channel (TALK) Phase 4 - resting membrane potential
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS			Apolipoprotein B levels ( 32203549) Cholesterol, total ( 24097068)
Interacting Genes		15 interacting genes: BHMT EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B HNRNPF HSCB KRT18 LMO4 MDFI NRF1 PAX2 PSME3 RBPMS	1 interacting genes: VKORC1
Entrez ID		583	89822
HPRD ID		05855	09566
Ensembl ID		ENSG00000125124	ENSG00000124780
Uniprot IDs		Q9BXC9	Q96T54
PDB IDs
Enriched GO Terms of Interacting Partners?
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