BBS2 and GOT2

Data Source:
BioGRID (genetic interference)

		BBS2	GOT2
Description		Bardet-Biedl syndrome 2	glutamic-oxaloacetic transaminase 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Microvillus Membrane Motile Cilium Stereocilium BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Plasma Membrane Cell Surface T-tubule Protein-containing Complex Perikaryon Extracellular Exosome
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding	RNA Binding L-aspartate:2-oxoglutarate Aminotransferase Activity Phospholipid Binding Kynurenine-oxoglutarate Transaminase Activity Amino Acid Binding Enzyme Binding Pyridoxal Phosphate Binding Identical Protein Binding
	Biological Process	Sperm Axoneme Assembly Visual Perception Protein Localization Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Multicellular Organism Growth Vasodilation Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cartilage Development Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly	Gluconeogenesis 2-oxoglutarate Metabolic Process Oxaloacetate Metabolic Process Aspartate Metabolic Process Aspartate Biosynthetic Process Aspartate Catabolic Process Glutamate Metabolic Process Female Pregnancy Lactation Cellular Amino Acid Biosynthetic Process Response To Muscle Activity Fatty Acid Transport 4-hydroxyproline Catabolic Process Glutamate Catabolic Process To Aspartate Glutamate Catabolic Process To 2-oxoglutarate Response To Insulin Response To Morphine Response To Ethanol Glyoxylate Metabolic Process L-kynurenine Metabolic Process
Pathways		BBSome-mediated cargo-targeting to cilium	Degradation of cysteine and homocysteine Glyoxylate metabolism and glycine degradation Gluconeogenesis Aspartate and asparagine metabolism Glutamate and glutamine metabolism
Drugs			Pyridoxal phosphate Aspartic acid Glutamic acid Cysteine 4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate
Diseases		Bardet-Biedl syndrome (BBS)
GWAS			Aortic root size ( 21223598) Aspartate aminotransferase levels ( 29403010) Automobile speeding propensity ( 30643258) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Impulsivity (attentional) ( 30718321) Metabolite levels ( 23823483) QT interval ( 19305408) Triglyceride levels ( 32203549) Urinary metabolite levels in chronic kidney disease ( 31959995) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		15 interacting genes: BHMT EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B HNRNPF HSCB KRT18 LMO4 MDFI NRF1 PAX2 PSME3 RBPMS	10 interacting genes: APCS CCL21 GAPDH GLRX GLUD1 HSPA8 MDH2 PC THOC7 ZDHHC6
Entrez ID		583	2806
HPRD ID		05855	00684
Ensembl ID		ENSG00000125124	ENSG00000125166
Uniprot IDs		Q9BXC9	P00505
PDB IDs			5AX8
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?