BBS2 and SPTSSA

Data Source:
BioGRID (proximity labelling technology)

		BBS2	SPTSSA
Description		Bardet-Biedl syndrome 2	serine palmitoyltransferase small subunit A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Microvillus Membrane Motile Cilium Stereocilium BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Serine C-palmitoyltransferase Complex
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding	Serine C-palmitoyltransferase Activity Protein Binding
	Biological Process	Sperm Axoneme Assembly Visual Perception Protein Localization Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Multicellular Organism Growth Vasodilation Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cartilage Development Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly	Protein Localization Sphingolipid Biosynthetic Process Ceramide Biosynthetic Process
Pathways		BBSome-mediated cargo-targeting to cilium	Sphingolipid de novo biosynthesis
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS			Intraocular pressure ( 29785010 31959993)
Interacting Genes		15 interacting genes: BHMT EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B HNRNPF HSCB KRT18 LMO4 MDFI NRF1 PAX2 PSME3 RBPMS	8 interacting genes: CYSRT1 GET1 GLP1R HERPUD2 RHBDL1 TMEM31 TUBB3 VKORC1
Entrez ID		583	171546
HPRD ID		05855	16610
Ensembl ID		ENSG00000125124	ENSG00000165389
Uniprot IDs		Q9BXC9	Q969W0
PDB IDs
Enriched GO Terms of Interacting Partners?
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