PTPRM and BCCIP

Data Source:
BioGRID (pull down, enzymatic study, pull down)

		PTPRM	BCCIP
Description		protein tyrosine phosphatase receptor type M	BRCA2 and CDKN1A interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Adherens Junction Lamellipodium Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Centrosome Centriole Cytosol Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Mitotic Spindle Pole
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Identical Protein Binding Cadherin Binding	RNA Binding Protein Binding Kinase Regulator Activity
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Protein Dephosphorylation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Negative Regulation Of Endothelial Cell Migration Retina Layer Formation Negative Regulation Of Angiogenesis Neuron Projection Development Retinal Ganglion Cell Axon Guidance Peptidyl-tyrosine Dephosphorylation Response To Drug	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Cytoskeleton Organization DNA Repair Mitotic Spindle Organization Microtubule Anchoring Neuroendocrine Cell Differentiation Mitotic Spindle Assembly
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Benign childhood epilepsy with centro-temporal spikes ( 32580138) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Dialysis-related mortality ( 21546767) Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243) Glucose homeostasis traits ( 25524916) Hippocampal volume ( 29860282) Huntington's disease progression ( 28642124) Iris heterochromicity ( 30895295) Lateral ventricle temporal horn volume ( 31530798) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Recurrence of mild malaria attacks ( 31667592) Response to methotrexate in rheumatoid arthritis ( 24583629) Sitting height ratio ( 25865494)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		11 interacting genes: BCCIP CDH1 CTNNB1 CTNND1 IQGAP1 PCSK5 PPFIBP1 PTPRA PTPRK PTPRS RACK1	26 interacting genes: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDC42 CDKN1A CENPJ CSNK2B FCF1 H2BC15 ITSN2 MRPS9 PDGFB PTN PTPRM RAD51 RALY RPL23 RPL38 SRC TENT5A TP53 YY1 ZNF138 ZNF19
Entrez ID		5797	56647
HPRD ID		01479	16542
Ensembl ID		ENSG00000173482	ENSG00000107949
Uniprot IDs		P28827	Q9P287
PDB IDs		1RPM 2C9A 2V5Y
Enriched GO Terms of Interacting Partners?
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