PTPRM and PPFIBP1

Data Source:
HPRD (in vitro)

		PTPRM	PPFIBP1
Description		protein tyrosine phosphatase receptor type M	PPFIA binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Adherens Junction Lamellipodium Perinuclear Region Of Cytoplasm	Cytosol Plasma Membrane Focal Adhesion Presynaptic Active Zone
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Identical Protein Binding Cadherin Binding	Protein Binding Cadherin Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Protein Dephosphorylation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Negative Regulation Of Endothelial Cell Migration Retina Layer Formation Negative Regulation Of Angiogenesis Neuron Projection Development Retinal Ganglion Cell Axon Guidance Peptidyl-tyrosine Dephosphorylation Response To Drug	Cell Adhesion Neuromuscular Junction Development Synapse Organization
Pathways			Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Adult body size ( 32376654) Benign childhood epilepsy with centro-temporal spikes ( 32580138) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Dialysis-related mortality ( 21546767) Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243) Glucose homeostasis traits ( 25524916) Hippocampal volume ( 29860282) Huntington's disease progression ( 28642124) Iris heterochromicity ( 30895295) Lateral ventricle temporal horn volume ( 31530798) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Recurrence of mild malaria attacks ( 31667592) Response to methotrexate in rheumatoid arthritis ( 24583629) Sitting height ratio ( 25865494)	Cerebral cortical growth ( 29682794) Early-onset Parkinson's disease ( 28256260) Refractive error ( 32231278)
Interacting Genes		11 interacting genes: BCCIP CDH1 CTNNB1 CTNND1 IQGAP1 PCSK5 PPFIBP1 PTPRA PTPRK PTPRS RACK1	8 interacting genes: PBX2 PPFIA1 PPFIA2 PPFIA3 PTPRM S100A4 YWHAG YWHAQ
Entrez ID		5797	8496
HPRD ID		01479	04390
Ensembl ID		ENSG00000173482	ENSG00000110841
Uniprot IDs		P28827	A0A024RB02 Q86W92
PDB IDs		1RPM 2C9A 2V5Y
Enriched GO Terms of Interacting Partners?
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