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BCCIP and H2BC15
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
BCCIP
H2BC15
Description
BRCA2 and CDKN1A interacting protein
H2B clustered histone 15
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Centrosome
Centriole
Cytosol
Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex
Mitotic Spindle Pole
Nucleosome
Nucleus
Nucleoplasm
Cytosol
Extracellular Exosome
Molecular Function
RNA Binding
Protein Binding
Kinase Regulator Activity
DNA Binding
Protein Heterodimerization Activity
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Microtubule Cytoskeleton Organization
DNA Repair
Mitotic Spindle Organization
Microtubule Anchoring
Neuroendocrine Cell Differentiation
Mitotic Spindle Assembly
Nucleosome Assembly
Protein Ubiquitination
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
HDACs deacetylate histones
HATs acetylate histones
HATs acetylate histones
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Ub-specific processing proteases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
Deposition of new CENPA-containing nucleosomes at the centromere
G2/M DNA damage checkpoint
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
E3 ubiquitin ligases ubiquitinate target proteins
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Inhibition of DNA recombination at telomere
Amyloid fiber formation
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Red blood cell count (
32888494
)
Interacting Genes
26 interacting genes:
ABCB1
BARD1
BRCA2
CAPZB
CCDC33
CDC42
CDKN1A
CENPJ
CSNK2B
FCF1
H2BC15
ITSN2
MRPS9
PDGFB
PTN
PTPRM
RAD51
RALY
RPL23
RPL38
SRC
TENT5A
TP53
YY1
ZNF138
ZNF19
19 interacting genes:
BCCIP
EWSR1
FAM133A
FAM9A
H1-7
H2AB2
H2AB3
H2AC18
H2AC19
H2AC4
H2AC8
MACROH2A1
MACROH2A2
NKAPD1
PRR13
RPL22
SPANXN2
SREK1IP1
TSPYL2
Entrez ID
56647
8341
HPRD ID
16542
11899
Ensembl ID
ENSG00000107949
ENSG00000233822
Uniprot IDs
Q9P287
A0A024RCJ9
Q99877
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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