POLD4 and WRNIP1

Data Source:
HPRD (in vitro)

		POLD4	WRNIP1
Description		DNA polymerase delta 4, accessory subunit	WRN helicase interacting protein 1
Image
GO Annotations	Cellular Component	Nucleoplasm Delta DNA Polymerase Complex	Chromosome, Telomeric Region Nucleus Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	DNA-directed DNA Polymerase Activity Protein Binding	DNA Binding Protein Binding ATP Binding Enzyme Activator Activity ATPase Activity Single-stranded DNA Helicase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Telomere Maintenance DNA Synthesis Involved In DNA Repair DNA-dependent DNA Replication Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Gap Filling Mismatch Repair Translesion Synthesis Telomere Maintenance Via Semi-conservative Replication Nucleotide-excision Repair, DNA Incision DNA Damage Response, Detection Of DNA Damage	DNA Synthesis Involved In DNA Repair DNA-dependent DNA Replication Regulation Of DNA Repair Regulation Of DNA-dependent DNA Replication Initiation DNA Duplex Unwinding Innate Immune Response Regulation Of Catalytic Activity
Pathways		Recognition of DNA damage by PCNA-containing replication complex Polymerase switching on the C-strand of the telomere Processive synthesis on the C-strand of the telomere Telomere C-strand (Lagging Strand) Synthesis Removal of the Flap Intermediate from the C-strand Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Plateletcrit ( 32888494)
Interacting Genes		9 interacting genes: DTL PCNA POLD1 POLD2 POLD3 POLE RNF8 SEC23IP WRNIP1	12 interacting genes: ABL1 ERBB3 PCNA PIK3R3 PIN1 POLD1 POLD2 POLD4 TOLLIP TRIM14 UBC WRN
Entrez ID		57804	56897
HPRD ID		17873	10494
Ensembl ID		ENSG00000175482	ENSG00000124535
Uniprot IDs		A0A024R5D7 Q6NSD7 Q9HCU8	Q96S55
PDB IDs		6HVO 6S1M 6S1N 6S1O 6TNY 6TNZ	3VHS 3VHT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?