SCUBE2 and STK33

Data Source:
BioGRID (biochemical)

		SCUBE2	STK33
Description		signal peptide, CUB domain and EGF like domain containing 2	serine/threonine kinase 33
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface	Nucleus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding Lipid Binding	Protein Serine/threonine Kinase Activity ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Signal Transduction Multicellular Organism Development	Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Protein Autophosphorylation
Pathways		Release of Hh-Np from the secreting cell
Drugs			Fostamatinib
Diseases
GWAS		β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Brain morphology (MOSTest) ( 32665545) Hand grip strength (Mahalanobis distance) ( 32235003)	Adult body size ( 32376654) Body mass index ( 26426971 19079261 28892062 28448500) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body mass index x sex x age interaction (4df test) ( 26426971) Fruit consumption ( 32066663) Intake of total sugars ( 31005972) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Small cell lung carcinoma ( 28604730)
Interacting Genes		1 interacting genes: SCUBE1	5 interacting genes: APP GLYCTK HPD USP15 USP5
Entrez ID		57758	65975
HPRD ID		18030	09642
Ensembl ID		ENSG00000175356	ENSG00000130413
Uniprot IDs		B3KS09 Q9NQ36	B3KS39 B4DDH2 F8WAK5 Q9BYT3
PDB IDs
Enriched GO Terms of Interacting Partners?
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