CACHD1 and PEBP1

Data Source:
HPRD (two hybrid)

		CACHD1	PEBP1
Description		cache domain containing 1	phosphatidylethanolamine binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Voltage-gated Calcium Channel Complex	Nucleus Cytosol Extracellular Exosome
	Molecular Function	Voltage-gated Calcium Channel Activity	RNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding ATP Binding Phosphatidylethanolamine Binding Enzyme Binding Protein Kinase Binding
	Biological Process	Calcium Ion Transmembrane Transport	MAPK Cascade Negative Regulation Of Endopeptidase Activity Negative Regulation Of MAPK Cascade
Pathways			MAP2K and MAPK activation Negative regulation of MAPK pathway Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Signaling downstream of RAS mutants
Drugs			Copper
Diseases
GWAS		Gut microbiota relative abundance (Bifidobacterium) ( 33208821)	Blood protein levels ( 30072576) Morphine dose requirement in tonsillectomy and adenoidectomy surgery ( 24909733)
Interacting Genes		5 interacting genes: BICRAL PEBP1 RANBP10 XAB2 ZMIZ1	23 interacting genes: BRAF CACHD1 CHUK ERBB2 GRK2 GSDMB IKBKB MAP2K1 MAP3K14 MAP3K7 MAPK1 MED10 NKX3-1 NR2C2 PICK1 PPARD PRKCA PRKCB PRKCD PRKCG PRKCZ RAF1 STC2
Entrez ID		57685	5037
HPRD ID		13874	06850
Ensembl ID		ENSG00000158966	ENSG00000089220
Uniprot IDs		A0A0A0MQY7 A0A3B3ISH2 Q5VU97	D9IAI1 P30086
PDB IDs			1BD9 1BEH 2L7W 2QYQ
Enriched GO Terms of Interacting Partners?
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